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4-Hydroxycinnamic Acid
CAS No. 7400-08-0
- Purity: 99.5%
- Appearance: Off-white Powder
- Package: 25kg/bag
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4-Hydroxycinnamic Acid
- CAS No.7400-08-0
- Synonyms: 4-Hydroxycinnamic acid; 4-Hydroxycinnamic acid; P-HYDROXYCINNAMIC ACID; TRANS-4-COUMARIC ACID; TRANS-P-COUMARIC ACID; PHCA; P-CUMARIC ACID; TRANS-P-CUMARIC ACID; 4-hydroxylcinnamic acid; 3-(4-HYDROXYPHENYL)ACRYLIC ACID
- CBNumber: CB9164396
- Molecular Formula: C9H8O3
- Melting point: 214 °C (dec.)(lit.)
- Boiling point: 251.61°C (rough estimate)
- Density 1.2132 (rough estimate)
- Refractive index 1.5380 (estimate)
- Storage temp.：Store below +30°C.
- Solubility: Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
- pka: 4.65±0.10(Predicted)
- Form: Solid
- Color: White to Off-White
- Stability: Light Sensitive
- InChI: InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)
- InChIKey: NGSWKAQJJWESNS-UHFFFAOYSA-N
SMILES C(O)(=O)C=CC1=CC=C(O)C=C1 - LogP: 1.790
- FDA UNII: IBS9D1EU3J
- NIST Chemistry: Reference 2-Propenoic acid, 3-(4-hydroxyphenyl)-(7400-08-0)
- EPA Substance: Registry System p-Hydroxycinnamic acid (7400-08-0)
- Hazard Codes Xi
Chemical Properties
Light yellow to beige crystalline powder with aroma, soluble in methanol, ethanol, DMSO and other organic solvents, derived from synthesis.
Uses
4-Hydroxycinnamic acid is the hydroxy derivative of Cinnamic Acid with antioxidant properties. It is a is a major component of lignocellulose. Studies suggest that 4-Hydroxycinnamic acid may reduce the risk of cancer by reducing the formation of carcinogenic nitrosamines. A recent study reports that 4-Hydroxycinnamic acid may act as a chemical castrator in bees by altering the epression of genes required for ovary development. This compound is common in pollen a major constituent of the worker bee diet, but it is not found in queen bees’royal jelly.
Application
p-Hydroxycinnamic acid is mainly used as an intermediate in the pharmaceutical and perfume industries. It can react with dimethyl sulfate to produce p-anisaldehyde, react with acetaldehyde to produce p-hydroxycinnamaldehyde, and further oxidize it to produce cinnamic acid. This product can be directly oxidized to produce 4-Hydroxybenzoic acid and reduction to produce 4-Hydroxybenzyl alcohol.
Definition
ChEBI: 4-coumaric acid is a coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. It has a role as a plant metabolite. It is a conjugate acid of a 4-coumarate.
Hazard
Moderately toxic.
Safety Profile
Moderarely toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes.
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- Etherification Reaction
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As a pioneer in the sector, Shanxi Yongjin Group is dedicated to delivering exceptional environmental protection and post-processing machinery. This commitment is aimed at fulfilling both national and local regulations, thereby safeguarding the lives, property, and environment of the local populace.
- Water treatment: circulating water, -15℃ chilled water, steam, primary water, desalinated water
- Gas treatment: compressed air, nitrogen, oxygen, hydrogen
- Sewage treatment
- VOCs absorption treatment
As a pioneer in the sector, Shanxi Yongjin Group is dedicated to delivering exceptional environmental protection and post-processing machinery. This commitment is aimed at fulfilling both national and local regulations, thereby safeguarding the lives, property, and environment of the local populace.
- Water treatment: circulating water, -15℃ chilled water, steam, primary water, desalinated water
- Gas treatment: compressed air, nitrogen, oxygen, hydrogen
- Sewage treatment
- VOCs absorption treatment
As a pioneer in the sector, Shanxi Yongjin Group is dedicated to delivering exceptional environmental protection and post-processing machinery. This commitment is aimed at fulfilling both national and local regulations, thereby safeguarding the lives, property, and environment of the local populace.
- Water treatment: circulating water, -15℃ chilled water, steam, primary water, desalinated water
- Gas treatment: compressed air, nitrogen, oxygen, hydrogen
- Sewage treatment
- VOCs absorption treatment
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As a pioneer in the sector, Shanxi Yongjin Group is dedicated to delivering exceptional environmental protection and post-processing machinery. This commitment is aimed at fulfilling both national and local regulations, thereby safeguarding the lives, property, and environment of the local populace.
- Water treatment: circulating water, -15℃ chilled water, steam, primary water, desalinated water
- Gas treatment: compressed air, nitrogen, oxygen, hydrogen
- Sewage treatment
- VOCs absorption treatment
As a pioneer in the sector, Shanxi Yongjin Group is dedicated to delivering exceptional environmental protection and post-processing machinery. This commitment is aimed at fulfilling both national and local regulations, thereby safeguarding the lives, property, and environment of the local populace.
- Water treatment: circulating water, -15℃ chilled water, steam, primary water, desalinated water
- Gas treatment: compressed air, nitrogen, oxygen, hydrogen
- Sewage treatment
- VOCs absorption treatment
As a pioneer in the sector, Shanxi Yongjin Group is dedicated to delivering exceptional environmental protection and post-processing machinery. This commitment is aimed at fulfilling both national and local regulations, thereby safeguarding the lives, property, and environment of the local populace.
- Water treatment: circulating water, -15℃ chilled water, steam, primary water, desalinated water
- Gas treatment: compressed air, nitrogen, oxygen, hydrogen
- Sewage treatment
- VOCs absorption treatment
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4-Hydroxybenzaldehyde
- CAS No. 7400-08-0
- Purity: 99.5%
- Appearance: off-white color
- Packaging: 25kg/drum
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