{"id":4850,"date":"2025-02-07T16:33:04","date_gmt":"2025-02-07T16:33:04","guid":{"rendered":"https:\/\/biovanix.com\/?page_id=4850"},"modified":"2025-02-07T17:07:49","modified_gmt":"2025-02-07T17:07:49","slug":"smb-chromatography-system","status":"publish","type":"page","link":"https:\/\/biovanix.com\/de\/smb-chromatography-system\/","title":{"rendered":"SMB Chromatographie-System"},"content":{"rendered":"
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SMB (Simulated Moving Bed) Chromatographie-System<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Innovative Solutions for Efficient Separation<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Biovanix SMB (Simulated Moving Bed) Chromatography System is an advanced continuous chromatography separation technology widely used in chemical, pharmaceutical, and food industries. By simulating the movement of the stationary phase, the SMB system achieves highly efficient and stable separation effects, significantly improving production efficiency and product quality.<\/p>

Biovanix SMB system connects multiple chromatography columns into a loop system, divided into functional zones such as adsorption, elution, and regeneration. By periodically switching valves, the stationary phase is made to \u201cmove\u201d relative to the mobile phase, achieving continuous sample injection, separation, and collection.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Vorteile<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Hoher Wirkungsgrad<\/strong><\/h3>
The SMB system can increase production efficiency by 3-8 times compared to traditional single-column chromatography.<\/div>

Low Solvent Consumption<\/strong><\/h3>
Optimized separation processes reduce solvent usage by 20-50%.<\/div>

High Purity and High Recovery Rate<\/strong><\/h3>
Product purity can reach nearly 100%, with a recovery rate of up to 100%.<\/div>

Continuous Operation<\/strong><\/h3>
Achieves 24\/7 uninterrupted operation, reducing labor costs.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Technische Spezifikation<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Number of Columns<\/strong>\uff1a4-12.<\/div>
Number of DAC Columns<\/strong>\uff1a2-4.<\/div>
Bereich der Durchflussrate<\/strong>\uff1a0.1-10 L\/min.<\/div>
Operating Pressure<\/strong>\uff1a0.1-10 MPa.<\/div>
Temperature Range<\/strong>\uff1a5-80\u00b0C.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Personalisierung<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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We offer comprehensive technical support and services, including system installation, commissioning, training, and after-sales maintenance, to ensure that customers can operate the SMB system smoothly.<\/p>

1. Separation Efficiency<\/strong><\/h3>
  • Reinheit<\/strong>: SMB chromatography is designed to achieve high-purity separation, with product purity often reaching above 99%.<\/div><\/li>
  • Recovery Rate<\/strong>: With optimized operating conditions, the recovery rate in SMB chromatography can approach 100%.<\/div><\/li><\/ul>

    2. Operating Parameters<\/strong><\/h3>
    • Durchflussmenge<\/strong>: The flow rate of the mobile phase is a critical parameter, typically optimized based on the separation target. The flow rate range is generally between 0.1-10 L\/min.<\/div><\/li>
    • Switching Time<\/strong>: The valve switching time is an important operational parameter in SMB systems, determining the “movement” speed of the stationary phase relative to the mobile phase. The selection of switching time needs to be optimized based on the adsorption characteristics of the substances being separated.<\/div><\/li>
    • Feed Rate<\/strong>: The amount of feed introduced into the system directly affects separation efficiency and the system’s production capacity.<\/div><\/li><\/ul>

      3. System Configuration<\/strong><\/h3>
      • Number of Columns<\/strong>: SMB systems typically consist of 4-12 chromatographic columns.<\/div><\/li>
      • Column Dimensions<\/strong>: Including column length, diameter, and packing volume, these parameters influence separation effectiveness and the system’s processing capacity.<\/div><\/li><\/ul>

        4. Economic Indicators<\/strong><\/h3>
        • Solvent Consumption<\/strong>: Compared to traditional batch chromatography, SMB chromatography can reduce solvent usage by 20-50%.<\/div><\/li>
        • Adsorbent Usage<\/strong>: SMB chromatography can save up to 50% of adsorbent.<\/div><\/li>
        • Operating Cost<\/strong>: Long-term operating costs can be reduced by 50%, primarily due to the savings in solvent and adsorbent usage.<\/div><\/li><\/ul>

          5. Control and Optimization<\/strong><\/h3>
          • Control Strategy<\/strong>: Modern SMB systems often employ advanced control strategies, such as Model Predictive Control (MPC) and Moving Horizon Estimation (MHE), to achieve efficient separation.<\/div><\/li>
          • Optimization Parameters<\/strong>: These include isotherm models, mass transfer resistances, and cycle switching times.<\/div><\/li><\/ul>

            6. Other Indicators<\/strong><\/h3>
            • Temperature Range<\/strong>: Typically between 5-80\u00b0C, depending on the nature of the substances being separated.<\/div><\/li>
            • Druckbereich<\/strong>: Operating pressure is generally between 0.1-10 MPa.<\/div><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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              Anmeldung<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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              Chemical Industry<\/strong><\/h3>
              Separation of xylene isomers.<\/div>

              Pharmaceutical Industry<\/strong><\/h3>
              Chiral drug separation.<\/div>

              Food Industry<\/strong><\/h3>
              Separation of fructose and glucose.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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              Warum Biovanix w\u00e4hlen?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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              Fachwissen und Erfahrung<\/h3>
              Mit jahrelanger Erfahrung in der Fluidtransferbranche verf\u00fcgen wir \u00fcber das Fachwissen und die Kenntnisse, um Ihnen die besten L\u00f6sungen f\u00fcr Ihre spezifischen Anforderungen zu bieten. Unser Team von Fachleuten unterst\u00fctzt Sie bei der Auswahl der richtigen Kolbenpumpe f\u00fcr Ihre Anwendung und sorgt f\u00fcr eine erfolgreiche Umsetzung.<\/div>
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              Qualit\u00e4t und Verl\u00e4sslichkeit<\/h3>
              Wir sind bestrebt, Ihnen Produkte und Dienstleistungen von h\u00f6chster Qualit\u00e4t zu bieten. Unsere Plungerpumpe wird nach den h\u00f6chsten Standards entwickelt und hergestellt, um eine zuverl\u00e4ssige Leistung und lange Haltbarkeit zu gew\u00e4hrleisten.<\/div>
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              Kundenbetreuung<\/h3>
              Bei [Name Ihres Unternehmens] steht die Zufriedenheit unserer Kunden an erster Stelle. Unser engagiertes Kundenserviceteam steht Ihnen jederzeit zur Verf\u00fcgung, um Sie bei Fragen oder Problemen zu unterst\u00fctzen. Vom technischen Support bis hin zum Kundendienst sorgen wir f\u00fcr einen reibungslosen und problemlosen Ablauf.<\/div>
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              Kundenspezifische L\u00f6sungen<\/h3>
              Wir wissen, dass jede Anwendung einzigartig ist. Deshalb bieten wir kundenspezifische L\u00f6sungen an, die auf Ihre speziellen Bed\u00fcrfnisse zugeschnitten sind. Ganz gleich, ob Sie eine Standard-Plungerpumpe oder eine kundenspezifische L\u00f6sung ben\u00f6tigen, wir sind in der Lage, Ihre Anforderungen zu erf\u00fcllen.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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              Kontakt<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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              Sind Sie bereit, die Leistung und Zuverl\u00e4ssigkeit unserer Plungerpumpe zu erleben? Kontaktieren Sie uns noch heute, um mehr \u00fcber unsere Produkte und Dienstleistungen zu erfahren. Unser Expertenteam ist bereit, Sie zu unterst\u00fctzen und Ihnen die beste L\u00f6sung f\u00fcr den Fl\u00fcssigkeitstransfer f\u00fcr Ihre Anwendung zu bieten.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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