{"id":4878,"date":"2025-02-08T13:13:16","date_gmt":"2025-02-08T13:13:16","guid":{"rendered":"https:\/\/biovanix.com\/?page_id=4878"},"modified":"2025-02-08T15:04:24","modified_gmt":"2025-02-08T15:04:24","slug":"oligo-dt25-affinity-chromatography-resin","status":"publish","type":"page","link":"https:\/\/biovanix.com\/fr\/oligo-dt25-affinity-chromatography-resin\/","title":{"rendered":"R\u00e9sine de chromatographie d'affinit\u00e9 Oligo dT(25)"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"4878\" class=\"elementor elementor-4878\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f2b3486 e-flex e-con-boxed e-con e-parent\" data-id=\"f2b3486\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1af111e elementor-widget elementor-widget-heading\" data-id=\"1af111e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">R\u00e9sine de chromatographie d'affinit\u00e9 Oligo dT(25)<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6964417 elementor-widget elementor-widget-text-editor\" data-id=\"6964417\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Biovanix Oligo dT(25) Affinity Resin<\/strong>\u00a0is a cutting-edge solution designed for the purification and isolation of mRNA from in vitro transcription (IVT) manufacturing processes. This advanced resin selectively captures mRNA via its polyadenylated (polyA) tail, effectively separating it from other components of the transcription reaction, such as enzymes and plasmid DNA.<\/p><p>Perfectly suited for large-scale downstream purification,\u00a0<strong>Biovanix Oligo dT(25) Affinity Resin<\/strong>\u00a0is a key enabler for vaccine and gene therapy applications, offering unmatched selectivity and capacity to meet the demands of modern biopharmaceutical manufacturing.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-63335b8 e-flex e-con-boxed e-con e-parent\" data-id=\"63335b8\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b528e69 elementor-widget elementor-widget-text-editor\" data-id=\"b528e69\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2>Features<\/h2><h4><strong>1. Selective mRNA Capture<\/strong><\/h4><ul><li><strong>PolyA Tail Specificity:<\/strong>\u00a0Targets mRNA with high selectivity, ensuring effective removal of plasmid DNA and other IVT components.<\/li><li><strong>Simple Salt and Water Elution:<\/strong>\u00a0Streamlined purification process with minimal complexity.<\/li><\/ul><h4><strong>2. Scalable Solution<\/strong><\/h4><ul><li><strong>Excellent Scalability:<\/strong>\u00a0Designed for seamless transition from lab-scale to large-scale production.<\/li><li><strong>High Capacity:<\/strong>\u00a0Meets the demands of high-yield mRNA manufacturing.<\/li><\/ul><h4><strong>3. Non-Animal Derived<\/strong><\/h4><ul><li><strong>Synthetic Manufacturing Process:<\/strong>\u00a0Biovanix oligo ligands are free of animal components, ensuring compliance with regulatory requirements and ethical standards.<\/li><\/ul><h4><strong>4. Simplified Workflow<\/strong><\/h4><ul><li><strong>Reduced Complexity:<\/strong>\u00a0Eliminates the need for multiple purification steps, maximizing efficiency and reducing downstream processing complexity.<\/li><li><strong>Consistent Performance:<\/strong>\u00a0Reliable results across different scales and production batches.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bd1a46c e-flex e-con-boxed e-con e-parent\" data-id=\"bd1a46c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-be95407 elementor-widget elementor-widget-text-editor\" data-id=\"be95407\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"fl-row fl-row-fixed-width fl-row-bg-color fl-node-60f5336b77e5a fl-row-default-height fl-row-align-center nitro-offscreen\" data-node=\"60f5336b77e5a\"><div class=\"fl-row-content-wrap\"><div class=\"fl-row-content fl-row-fixed-width fl-node-content\"><div class=\"fl-col-group fl-node-60f5336b7a7d0\" data-node=\"60f5336b7a7d0\"><div class=\"fl-col fl-node-60f5336b7a866 fl-col-bg-color\" data-node=\"60f5336b7a866\"><div class=\"fl-col-content fl-node-content\"><div class=\"fl-module fl-module-rich-text fl-node-60f5336b77c2b\" data-node=\"60f5336b77c2b\"><div class=\"fl-module-content fl-node-content\"><div class=\"fl-rich-text\"><h2><strong>Specification<\/strong><\/h2><table width=\"627\"><tbody><tr><td width=\"172\"><strong>Characteristic<\/strong><\/td><td width=\"455\"><strong>Description<\/strong><\/td><\/tr><tr><td width=\"172\"><strong>Matrice de soutien<\/strong><\/td><td width=\"455\">Cross-linked poly(styrene-divinylbenzene)<\/td><\/tr><tr><td width=\"172\"><strong>Taille moyenne des particules<\/strong><\/td><td width=\"455\">50 um<\/td><\/tr><tr><td width=\"172\"><strong>Average Pore Size<\/strong><\/td><td width=\"455\">200 nm<\/td><\/tr><tr><td width=\"172\"><strong>Surface Functionality<\/strong><\/td><td width=\"455\">poly(dT) 25mer with proprietary linker<\/td><\/tr><tr><td width=\"172\"><strong>Densit\u00e9 du ligand<\/strong><\/td><td width=\"455\">0.3 umol\/ml<\/td><\/tr><tr><td width=\"172\"><strong>Mechanical Resistance<\/strong><\/td><td width=\"455\">70 bar (1,000 psi; 7 MPa)<\/td><\/tr><tr><td width=\"172\"><strong>Thermal Stability<\/strong><\/td><td width=\"455\">allows sample denaturing at 65\u00b0C if needed<\/td><\/tr><tr><td width=\"172\"><strong>Gamme de pH<\/strong><\/td><td width=\"455\">2-13<\/td><\/tr><tr><td width=\"172\"><strong>Ionic Strength Range<\/strong><\/td><td width=\"455\">0 to 5 M, all common salts<\/td><\/tr><tr><td width=\"172\"><strong>R\u00e9sistance chimique<\/strong><\/td><td width=\"455\">Common agents for mRNA purification, include 0.5 M NaOH, 2 M MgCl2, 20 mM EDTA. Water, 0 to 100% alcohol, acetonitrile, 2 M acetic acid, 1 M HCl, and other common organic solvents<\/td><\/tr><tr><td width=\"172\"><strong>Stockage<\/strong><\/td><td width=\"455\">18-20% ethanol<\/td><\/tr><\/tbody><\/table><h3>\u00a0<\/h3><h3><strong>Chemical &amp; Thermal Resistance<\/strong><\/h3><table><tbody><tr><td width=\"148\"><strong>Gamme de pH<\/strong><\/td><td width=\"399\">2\u201313<\/td><\/tr><tr><td width=\"148\"><strong>Ionic Strength Range<\/strong><\/td><td width=\"399\">0 to 5 M, all common salts<\/td><\/tr><tr><td width=\"148\"><strong>Buffer Additives<\/strong><\/td><td width=\"399\">Common agents for mRNA purification, include 0.5 M NaOH, 2 MMgCl2, 20 mM EDTA.<p>\u00a0<\/p><p>Do not expose to strong oxidizers (such as hypochlorite), oxidizing acids (such as nitric), strong reducing agents (such as sulfite), acetone, THF, or benzyl alcohol.<\/p><\/td><\/tr><tr><td width=\"148\"><strong>Solvents<\/strong><\/td><td width=\"399\">Water, 0 to 100% alcohol, acetonitrile, 2 M acetic acid, 1 M HCl, and other common organic solvents.<p>\u00a0<\/p><p>Do not expose to strong oxidizers (such as hypochlorite), oxidizing acids (such as nitric), strong reducing agents (such as sulfite), acetone, benzyl alcohol, or THF.<\/p><\/td><\/tr><tr><td width=\"148\"><strong>Flow rate<\/strong><\/td><td width=\"399\">Adjust flow rate depending on performance. Do not exceed upper-pressure limitations.<\/td><\/tr><\/tbody><\/table><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f8781d e-flex e-con-boxed e-con e-parent\" data-id=\"7f8781d\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f583519 elementor-widget elementor-widget-text-editor\" data-id=\"f583519\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><strong>Benefits at a Glance<\/strong><\/h2><h4><strong>High Efficiency<\/strong><\/h4><p>Rapid and efficient mRNA purification.<\/p><h4><strong>Scalable Process<\/strong><\/h4><p>Easily adaptable to large-scale manufacturing.<\/p><h4><strong>Conformit\u00e9 r\u00e9glementaire<\/strong><\/h4><p>Non-animal derived and synthetic manufacturing process.<\/p><h4><strong>Cost-Effective<\/strong><\/h4><p>Simplified workflow reduces operational complexity and costs.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b527727 e-flex e-con-boxed e-con e-parent\" data-id=\"b527727\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f312b27 elementor-widget elementor-widget-text-editor\" data-id=\"f312b27\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><strong>Applications<\/strong><\/h2><h4><strong>Vaccine Production<\/strong><\/h4><p>Efficient purification of mRNA vaccines.<\/p><h4><strong>Gene Therapy<\/strong><\/h4><p>Scalable production of mRNA for therapeutic applications.<\/p><h4><strong>IVT Manufacturing<\/strong><\/h4><p>Streamlined isolation of mRNA from transcription reaction mixtures.<\/p><h4><strong>Plasmid DNA Removal<\/strong><\/h4><p>Effective elimination of plasmid DNA and other IVT components.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7c1e95b e-flex e-con-boxed e-con e-parent\" data-id=\"7c1e95b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36532a3 elementor-widget elementor-widget-text-editor\" data-id=\"36532a3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><strong>Why Choose Biovanix Oligo dT(25) Affinity Resin?<\/strong><\/h2><h4><strong>Efficient mRNA Purification<\/strong><\/h4><p>Achieve high-purity mRNA with minimal impurities.<\/p><h4><strong>Cost-Effective<\/strong><\/h4><p>Reduced operational complexity and increased productivity lower overall production costs.<\/p><h4><strong>Conformit\u00e9 r\u00e9glementaire<\/strong><\/h4><p>Non-animal derived and synthetic manufacturing ensure compliance with global standards.<\/p><h4><strong>Versatile Application<\/strong><\/h4><p>Ideal for a wide range of mRNA constructs used in vaccines, gene therapies, and other biopharmaceuticals.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1dab938 e-flex e-con-boxed e-con e-parent\" data-id=\"1dab938\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e8fc8cd elementor-widget elementor-widget-heading\" data-id=\"e8fc8cd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Customer Testimonial<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f90b26b elementor-widget elementor-widget-text-editor\" data-id=\"f90b26b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>&#8220;Biovanix InertShell Chromatography Resin has transformed our virus purification process. The dual functionality and high selectivity have significantly improved our yields and purity levels, making it an essential tool in our testings.&#8221;<\/em><br \/><strong>\u2013 Alex, Developer, AA Biopharma<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Oligo dT(25) Affinity Chromatography Resin Biovanix Oligo dT(25) Affinity Resin\u00a0is a cutting-edge solution designed for the purification and isolation of mRNA from in vitro transcription (IVT) manufacturing processes. This advanced resin selectively captures mRNA via its polyadenylated (polyA) tail, effectively separating it from other components of the transcription reaction, such as enzymes and plasmid DNA. [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-4878","page","type-page","status-publish","hentry"],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"trp-custom-language-flag":false,"woocommerce_thumbnail":false,"woocommerce_single":false,"woocommerce_gallery_thumbnail":false},"uagb_author_info":{"display_name":"biovanix.com","author_link":"https:\/\/biovanix.com\/fr\/author\/biovanix-com\/"},"uagb_comment_info":0,"uagb_excerpt":"Oligo dT(25) Affinity Chromatography Resin Biovanix Oligo dT(25) Affinity Resin\u00a0is a cutting-edge solution designed for the purification and isolation of mRNA from in vitro transcription (IVT) manufacturing processes. This advanced resin selectively captures mRNA via its polyadenylated (polyA) tail, effectively separating it from other components of the transcription reaction, such as enzymes and plasmid DNA.\u2026","aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.3 - aioseo.com -->\n\t<meta name=\"description\" content=\"Oligo dT(25) Affinity Chromatography Resin for the purification and isolation of mRNA from in vitro transcription (IVT) manufacturing processes. 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