HPLC Column & Bulk

For Analytical + Preparative HPLC

BioVanix HPLC column is meticulously engineered to meet the rigorous demands of modern chromatography. Designed for routine and complex analyses, these columns are essential for laboratories seeking reliability, efficiency, and precision.

Features and Advantages

  • Superior Separation Efficiency: Utilizing advanced silica technology, our columns ensure sharp peak shapes and high resolution.
  • Broad pH Stability: Capable of operating in a wide pH range, enhancing their versatility and durability.
  • High Loadability: Suitable for both analytical and preparative applications, with excellent sample recovery rates.
  • Chemical Resistance: Robust design that withstands aggressive solvents and mobile phase conditions.
  • Versatility: Compatible with a wide range of detectors and HPLC systems.

Applications

  • Pharmaceutical and Biotech Industries: For drug development, quality control, and bioanalysis.
  • Environmental Testing: For detecting pollutants and contaminants.
  • Food and Beverage Industry: For quality assurance and regulatory compliance.
  • Clinical Research: For biomarker discovery and clinical diagnostics.
  • Academic and Government Research: For cutting-edge research in chemistry and life sciences.

Biovanix Product List

Selection by Column Dimension

Depending on the scale and/or efficiency of the separation required, the table below can help you to choose a column by the most appropriate inner diameter (I.D.) and column length for your needs.

Which column length is best for my needs?

  • If you want to maximize the speed of your application → 20 mm to 75 mm
  • If you want a balance of resolution and speed → 100 mm
  • If you want the best resolution possible → 150 mm
  • Also available in both analytical and semi-prep dimensions
Column dimension 
(I.D. × length in mm)
Application Reason
4.6/10/20×10 Guard-column Protection from mechanical contamination
Sample contaminated to low extent
4.6×30 Precolumn High capacity precolumn
2.1/3.0/4.0/4.6×30
2.1/3.0/4.0/4.6×50
Method development
Rapid HPLC and UHPLC (if pressure stable)
Short retention time
Rapid equilibration
Low solvent consumption (small I.D.)
Low pressure drop
2.1×100
2.1/3.0×150
High detection sensitivity (mass selectivity) Semi-micro column for low injection volumes and low peak
Low solvent consumption
4.6×100
4.0/4.6×125
4.0/4.6×150
Standard column Adequate performance for most applications (average performance 8000 – 10000 N/column)
2.1/3.0×250 High detection sensitivity
High performance separation
Semi-micro column for low injection volumes and low peak
Low solvent consumption
For complex samples
4.6×250 High robustness/higher tolerance to injection volume For very complex samples
10×150; 10×250 Semi-preparative For mg quantities of pure substance on lab scale
20/21.2/30/50×150
20/21.2/30/50×250
Preparative For g quantities of pure substance
BioVanix provide customized column size based on your needs

USP(US Pharmacopeia) Column Selection

USP Listing Packing Products
L1 Octadecyl silane chemically bonded to porous or non-porous silica or ceramic microparticles, 1.5 to 10 µm in diameter, or a monolithic rod C18
L3 Porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod Silica
L7 Octylsilane chemically bonded to totally or superficially porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod C8
L8 An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 1.5 to 10 µm in diameter, or a monolithic silica rod NH2
L9 Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, 3 to 10 μm in diameter SCX
L10 Nitrile groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod CN
L11 Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod Phenyl
L14 Silica gel having a chemically bonded strongly basic quaternary ammonium anion-exchange coating, 5 to 10 µm in diameter SAX
L17 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form, 6 to 12 µm in diameter Sugar-10H
L19 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form, 5 – 15 µm in diameter Sugar-10Ca
L20 Dihydroxypropane groups chemically bonded to porous silica or hybrid particles, 1.5 to 10 µm in diameter, or a monolithic silica rod HILIC-Diol
SEC
L26 Butyl silane chemically bonded to totally porous or superficially porous silica particles, 1.5 to 10 µm in diameter C4
L40 Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles, 3 µm to 20 µm in diameter Chiral OD
L43 Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer, 1.5 to 10 µm in diameter PFP
L51 Amylose tris-3,5-dimethylphenylcarbamate-coated, porous, spherical, silica particles, 3 to 10 µm in diameter Chiral AD
L58 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form, about 6 to 30 µm diameter Sugar-10Na
L60 Spherical, porous silica gel, 10 µm or less in diameter, the surface of which has been covalently modified with alkyl amide groups and endcapped Polar C18
L62 C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter C30
L68 Spherical, porous silica, 10 µm or less in diameter, the surface of which has been covalently modified with alkyl amide groups and not endcapped HILIC-Amide
Glycan
L78 A silane ligand that consists of both reversed-phase (an alkyl chain longer than C8) and anion-exchange (primary, secondary, tertiary, or quartenary amino groups) functional groups chemically bonded to porous or non-porous silica or ceramic micro-particles, 1.0 to 50 μm in diameter, or a monolithic rod SAA
L80 Cellulose tris(4-methylbenzoate)-coated, porous, spherical, silica particles, 5 – 20 µm in diameter Chiral OJ
L90 Amylose tris-[(S)-alpha-methylbenzylcarbamate] coated on porous, spherical silica particles, 3 to 10 µm in diameter Chiral AS
L118 Aqueous polymerized C18 groups on silica particles, 1.2 to 5 μm in diameter PAH

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