AutoPro Protein Chromatography System
Biovanix AutoPro Protein Chromatography System is a compact, modular system designed for the rapid purification of microgram to gram quantities of proteins, nucleic acids, vaccines, and polysaccharides. It combines high performance, precision, and flexibility to meet the demands of modern laboratory and industrial applications.
Features and Benefits
Enclosed Design
Prevents sample contamination and ensures a controlled environment.
Space-Saving
Stackable design for efficient storage.
High-Speed Operation
Low vibration and noise, minimizing sample loss.
Precision Control
Closed-loop control technology ensures accurate positioning and consistent results.
Bio-Inert Materials
All sample-contact components are made of biocompatible materials.
Fully Automated
The CDSystem operating system supports a wide range of chromatographic techniques and can be upgraded to enhance automation performance.
Key Features
Dual Pump System
High precision and reliability for gradient elution.
Fixed Single-Wavelength Detector
LED light source with a detection range of 280 nm, 260 nm, or 254 nm.
Temperature Sensor
Precision temperature monitoring and compensation.
Bubble Sensor
Monitors sample loading and bubble formation in the system.
Inline Filter
Ti alloy filter with a 20 μm pore size.
Dynamic Mixer
2 ml mixing chamber for efficient sample preparation.
Chromatographic Column Clamp
Supports two sets of columns for flexible configurations.
Technical Specification
| Model | Flow Rate Range | Pressure Range | Flow Accuracy |
|---|---|---|---|
| AutoPro25 | 0.001–25 ml/min | 0–27.5 MPa | ±1.5% |
| AutoPro100 | 0.001–100 ml/min | 0–10 MPa | ±1.5% |
| AutoPro150 | 0.001–150 ml/min | 0–5 MPa | ±1.5% |
Customization
Standard Configuration
- Dual pump system (AutoPro25/AutoPro100/AutoPro150)
- Three-position seven-port valve (software-controlled)
- Fixed single-wavelength detector (LED light source, ≥8000 hours lifespan)
- Temperature sensor (0–100°C, ±1% precision)
- Back pressure valve (20–200 psi adjustable)
- Inline filter (20 μm titanium alloy)
- Dynamic mixer (2 ml chamber)
- Chromatographic column clamp (two sets)
- Control system (computer, keyboard, mouse, Chinese/English software)
Optional Upgrades
- pH detector (0–14 pH range, ±0.1 precision)
- UV detector (fixed or variable wavelength)
- Outlet valve (two or nine channels)
- Component collector (supports 1–50 ml samples)
- Column valve (single or three-column configuration)
- Pressure monitoring (pre-column or front/back column)
- Sample pump (SP25D/SP100D/SP150D)
Application
Protein Purification
The AutoPro Protein Chromatography System is designed to efficiently purify proteins in quantities ranging from micrograms to grams. It supports various chromatographic techniques, such as ion exchange chromatography (IEX), size exclusion chromatography (SEC), and affinity chromatography, enabling high-yield and high-purity protein recovery.
Vaccine Purification
Vaccines require high purity and sterility to ensure safety and efficacy. The AutoPro system is ideal for vaccine purification due to its enclosed design and bio-inert materials, which prevent contamination and ensure consistent product quality.
Nucleic Acid Purification
AutoPro is well-suited for the purification of DNA, RNA, and other nucleic acids, which require sensitive handling to avoid degradation. The system’s advanced detection and control features ensure precise and reliable results.
Peptide Purification
Peptides are often purified in small quantities, requiring high precision and sensitivity. The AutoPro system’s ability to handle low flow rates and precise gradient elution makes it ideal for peptide purification.
Blood Products
Blood products, such as plasma proteins and clotting factors, require gentle and efficient purification to retain functionality. The AutoPro system’s gentle operation and high purity ensure the integrity of these critical biological products.
Polysaccharide Purification
Polysaccharides, such as those used in vaccines and biopharmaceuticals, require careful purification to maintain their complex structures. The AutoPro system’s flexibility and precision make it well-suited for this application.
