Ion Exchange IEX HPLC Column

Biovanix ion exchange IEX columns are based on modified silica particles and include weak cation exchange (WCX), strong cation exchange (SCX) and strong anion exchange (SAX) columns.

WCX columns are carboxylic acid modified silica particles that designed for separating charged variants in proteins, including monoclonal antibodies (mAbs) and related substances.

SCX columns are based on sulfonate-modified silica particles. These columns feature a strong cation exchange property and are suitable for cationic analytes.

SAX columns are based on quaternary ammonium modified silica particles that feature a strong anion exchange property and are suitable for separating anionic analytes.

Column Selection

Product Name	WCX Column	SCX Column	SAX Column
Functional Group	Carboxylic Acid	Sulfonic Acid	Quaternary Ammonium
Substrate	Monodispersed spherical PS/DVB particles
Particle Size	5 & 10 μm
Pore Size	Nonporous
Pressure Limit	4500 psi for 10 μm 5000 psi for 5 μm
Temperature Limit	60 ℃
pH Range	2-12