BioVanix DNA RP HPLC Column
BioVanix DNA RP HPLC Column is a family of high-performance, strong anion-exchange columns designed for separating oligonucleotides. Its column technology involves the creation of a hydrophilic quaternary amino functional layer on the surface of monodispersed, nonporous, spherical PS/DVB particles, in combination with a well-established column packing process.
During oligonucleotide synthesis, it is unavoidable to produce impurities with sizes close to target molecules such as
N-1 and N+1. To ensure drug quality, purity analysis is important. In this application, two short-chain oligonucleotides
(20 mer and 21 mer) with one unit difference are separated with baseline resolution (Rs=2.88) on the DNACore 1000
C18 column under IP-RP mode.
Parameter
Product Name | DNA RP Column |
Functional Group | Quaternary Ammonium |
Substrate | Monodispersed, spherical PS/DVB particles |
Particle Size | 5 μm |
Pore Size | Nonporous |
Pressure Limit | 5000 psi |
Temperature Limit | 80 ℃ |
pH Range | 2-12 |
Order Information
Product Name | 4.6-50mm | 4.6-100mm | 4.6-150mm | 4.6-250mm |
DNA RP | D301-050000-04605 | D301-050000-04610 | D301-050000-04615 | D301-050000-04625 |
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