Chromatography PSDVB Microspher
Biovanix offers ion exchange chromatography media based on a polymer matrix of PSDVB (styrene-divinylbenzene copolymer). After undergoing surface hydrophilic modification, ion exchange groups are covalently bonded. This medium has low non-specific adsorption, high mechanical strength, and is biocompatible with biologically active macromolecules, ensuring chemical stability and significantly improving purification efficiency.
The enhanced Poly50 matrix features superior mechanical resilience, chemical stability, and an open porous structure, with selections available for standard, large, and super-large pores. The surface is modified to be hydrophilic, reducing non-specific adsorption, and is designed for high flow rates, high resolution, and increased loading capacity. It is well-suited for separating and purifying biological macromolecules including monoclonal antibodies, viruses, and vaccines.
PS-DVB Particle Selection
| Product | Poly15 SP | Poly15 Q | Poly30 SP | Poly30 Q |
| Matrix | Monodisperse PS-DVB | |||
| Particle Size | 15um | 30um | ||
| Function Group | (-CH2)SO3- | -CH2N+(CH3)3 | (-CH2)SO3- | -CH2N+(CH3)3 |
| Ligand Density | 0.22meq/mL | 0.24meq/mL | 0.15meq/mL | 0.18meq/mL |
| Capacity | 80mg Lys/mL | 45mg BSA/mL | 60mg Lys/mL | 30mg BSA/mL |
| Flow Rate | 150~800cm/h | 250~1000cm/h | ||
| Max. Pressure | 8.0MPa | 5.0MPa | ||
| pH Stability | 2-12 | |||
| Chemical Stability | All commonly used buffers,1M acetic acid,1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea, and other commonly used organic solvents; Avoid exposure to strong oxidants. | |||
| Usage Temperature | 4~30°C | |||
| Storage | 2~30°C, 20% ethanol | |||
| Product | Poly 50M | |||
| Matrix | SP | Q | CM | DEAE |
| Particle Size | PS-DVB | |||
| Function Group | 50um | |||
| Pore Size | 100-150nm | |||
| Ligand Density | 0.15meq/mL | 0.16meq/mL | 0.15me q/mL | 0.16me q/mL |
| Capacity | >80mgLys | >100mg BSA | >80mgLys | >90mg BSA |
| Flow Rate | 300~1200cm/h | |||
| Max Pressure | 3.0MPa | |||
| pH Stability | 1-12 | |||
| Chemical Stability | All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants. | |||
| Usage Temperature | 4~30°C | |||
| Storage | 2~30°C, 20% ethanol | |||
| Product | Poly 50G | |||
| Matrix | SP | SP | SP | SP |
| Particle Size | PS-DVB | |||
| Function Group | 50um | |||
| Pore Size | 150-300nm | |||
| Ligand Density | 0.14me q/mL | 0.14me q/mL | 0.14me q/mL | 0.14me q/mL |
| Capacity | >70mg Lys | >70mg Lys | >70mg Lys | >70mg Lys |
| Flow Rate | 300~1200cm/h | |||
| Max Pressure | 2.0MPa | |||
| pH Stability | 1-12 | |||
| Chemical Stability | All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants. | |||
| Usage Temperature | 4~30°C | |||
| Storage | 2~30°C, 20% ethanol | |||
| Product | Poly 50V | |||
| Matrix | SP | SP | SP | SP |
| Particle Size | PS-DVB | |||
| Function Group | 50um | |||
| Pore Size | 300-400nm | |||
| Ligand Density | 0.12me q/mL | 0.12me q/mL | 0.12me q/mL | 0.12me q/mL |
| Capacity | >70mg Lys | >70mg Lys | >70mg Lys | >70mg Lys |
| Flow Rate | 300~1200cm/h | |||
| Max Pressure | 1.0MPa | |||
| pH Stability | 1-12 | |||
| Chemical Stability | All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants. | |||
| Usage Temperature | 4~30°C | |||
| Storage | 2~30°C, 20% ethanol | |||
