Chromatography PSDVB Microspher

Biovanix offers ion exchange chromatography media based on a polymer matrix of PSDVB (styrene-divinylbenzene copolymer). After undergoing surface hydrophilic modification, ion exchange groups are covalently bonded. This medium has low non-specific adsorption, high mechanical strength, and is biocompatible with biologically active macromolecules, ensuring chemical stability and significantly improving purification efficiency.

The enhanced Poly50 matrix features superior mechanical resilience, chemical stability, and an open porous structure, with selections available for standard, large, and super-large pores. The surface is modified to be hydrophilic, reducing non-specific adsorption, and is designed for high flow rates, high resolution, and increased loading capacity. It is well-suited for separating and purifying biological macromolecules including monoclonal antibodies, viruses, and vaccines.

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PS-DVB Particle Selection

Product Poly15 SP Poly15 Q Poly30 SP Poly30 Q
Matrix Monodisperse PS-DVB
Particle Size 15um 30um
Function Group (-CH2)SO3- -CH2N+(CH3)3 (-CH2)SO3- -CH2N+(CH3)3
Ligand Density 0.22meq/mL 0.24meq/mL 0.15meq/mL 0.18meq/mL
Capacity 80mg Lys/mL 45mg BSA/mL 60mg Lys/mL 30mg BSA/mL
Flow Rate 150~800cm/h 250~1000cm/h
Max. Pressure 8.0MPa 5.0MPa
pH Stability 2-12
  Chemical Stability All commonly used buffers,1M acetic acid,1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea, and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50M
Matrix SP Q CM DEAE
Particle Size PS-DVB
Function Group 50um
Pore Size 100-150nm
Ligand Density 0.15meq/mL 0.16meq/mL 0.15me q/mL 0.16me q/mL
Capacity >80mgLys >100mg BSA >80mgLys >90mg BSA
Flow Rate 300~1200cm/h
Max Pressure 3.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50G
Matrix SP SP SP SP
Particle Size PS-DVB
Function Group 50um
Pore Size 150-300nm
Ligand Density 0.14me q/mL 0.14me q/mL 0.14me q/mL 0.14me q/mL
Capacity >70mg Lys >70mg Lys >70mg Lys >70mg Lys
Flow Rate 300~1200cm/h
Max Pressure 2.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50V
Matrix SP SP SP SP
Particle Size PS-DVB
Function Group 50um
Pore Size 300-400nm
Ligand Density 0.12me q/mL 0.12me q/mL 0.12me q/mL 0.12me q/mL
Capacity >70mg Lys >70mg Lys >70mg Lys >70mg Lys
Flow Rate 300~1200cm/h
Max Pressure 1.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

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