HPLC Column & Bulk
For Analytical + Preparative HPLC
BioVanix HPLC column is meticulously engineered to meet the rigorous demands of modern chromatography. Designed for routine and complex analyses, these columns are essential for laboratories seeking reliability, efficiency, and precision.
Features and Advantages
- Superior Separation Efficiency: Utilizing advanced silica technology, our columns ensure sharp peak shapes and high resolution.
- Broad pH Stability: Capable of operating in a wide pH range, enhancing their versatility and durability.
- High Loadability: Suitable for both analytical and preparative applications, with excellent sample recovery rates.
- Chemical Resistance: Robust design that withstands aggressive solvents and mobile phase conditions.
- Versatility: Compatible with a wide range of detectors and HPLC systems.
Applications
- Pharmaceutical and Biotech Industries: For drug development, quality control, and bioanalysis.
- Environmental Testing: For detecting pollutants and contaminants.
- Food and Beverage Industry: For quality assurance and regulatory compliance.
- Clinical Research: For biomarker discovery and clinical diagnostics.
- Academic and Government Research: For cutting-edge research in chemistry and life sciences.
Product List
C18 Column & Bulk
C8 Column & Bulk
C4 Column
Phenyl Column & Bulk
SiO2 Column & Bulk
NH2/Amino Column & Bulk
CN/Cyano Column & Bulk
Diol Column & Bulk
Amide Column
HILIC Column
SEC Column
Sugar Column
DNA Column
Chrial Column
HIC Column
Guard Column
Selection by Column Dimension
Depending on the scale and/or efficiency of the separation required, the table below can help you to choose a column by the most appropriate inner diameter (I.D.) and column length for your needs.
Which column length is best for my needs?
- If you want to maximize the speed of your application → 20 mm to 75 mm
- If you want a balance of resolution and speed → 100 mm
- If you want the best resolution possible → 150 mm
- Also available in both analytical and semi-prep dimensions
| Column dimension (I.D. × length in mm) |
Application | Reason |
| 4.6/10/20×10 | Guard-column | Protection from mechanical contamination Sample contaminated to low extent |
| 4.6×30 | Precolumn | High capacity precolumn |
| 2.1/3.0/4.0/4.6×30 2.1/3.0/4.0/4.6×50 |
Method development Rapid HPLC and UHPLC (if pressure stable) |
Short retention time Rapid equilibration Low solvent consumption (small I.D.) Low pressure drop |
| 2.1×100 2.1/3.0×150 |
High detection sensitivity (mass selectivity) | Semi-micro column for low injection volumes and low peak Low solvent consumption |
| 4.6×100 4.0/4.6×125 4.0/4.6×150 |
Standard column | Adequate performance for most applications (average performance 8000 – 10000 N/column) |
| 2.1/3.0×250 | High detection sensitivity High performance separation |
Semi-micro column for low injection volumes and low peak Low solvent consumption For complex samples |
| 4.6×250 | High robustness/higher tolerance to injection volume | For very complex samples |
| 10×150; 10×250 | Semi-preparative | For mg quantities of pure substance on lab scale |
| 20/21.2/30/50×150 20/21.2/30/50×250 |
Preparative | For g quantities of pure substance |
| BioVanix provide customized column size based on your needs | ||
USP(US Pharmacopeia) Column Selection
| USP Listing | Packing | Products |
| L1 | Octadecyl silane chemically bonded to porous or non-porous silica or ceramic microparticles, 1.5 to 10 µm in diameter, or a monolithic rod | C18 |
| L3 | Porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod | Silica |
| L7 | Octylsilane chemically bonded to totally or superficially porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod | C8 |
| L8 | An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 1.5 to 10 µm in diameter, or a monolithic silica rod | NH2 |
| L9 | Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, 3 to 10 μm in diameter | SCX |
| L10 | Nitrile groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod | CN |
| L11 | Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod | Phenyl |
| L14 | Silica gel having a chemically bonded strongly basic quaternary ammonium anion-exchange coating, 5 to 10 µm in diameter | SAX |
| L17 | Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form, 6 to 12 µm in diameter | Sugar-10H |
| L19 | Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form, 5 – 15 µm in diameter | Sugar-10Ca |
| L20 | Dihydroxypropane groups chemically bonded to porous silica or hybrid particles, 1.5 to 10 µm in diameter, or a monolithic silica rod | HILIC-Diol SEC |
| L26 | Butyl silane chemically bonded to totally porous or superficially porous silica particles, 1.5 to 10 µm in diameter | C4 |
| L40 | Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles, 3 µm to 20 µm in diameter | Chiral OD |
| L43 | Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer, 1.5 to 10 µm in diameter | PFP |
| L51 | Amylose tris-3,5-dimethylphenylcarbamate-coated, porous, spherical, silica particles, 3 to 10 µm in diameter | Chiral AD |
| L58 | Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form, about 6 to 30 µm diameter | Sugar-10Na |
| L60 | Spherical, porous silica gel, 10 µm or less in diameter, the surface of which has been covalently modified with alkyl amide groups and endcapped | Polar C18 |
| L62 | C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter | C30 |
| L68 | Spherical, porous silica, 10 µm or less in diameter, the surface of which has been covalently modified with alkyl amide groups and not endcapped | HILIC-Amide Glycan |
| L78 | A silane ligand that consists of both reversed-phase (an alkyl chain longer than C8) and anion-exchange (primary, secondary, tertiary, or quartenary amino groups) functional groups chemically bonded to porous or non-porous silica or ceramic micro-particles, 1.0 to 50 μm in diameter, or a monolithic rod | SAA |
| L80 | Cellulose tris(4-methylbenzoate)-coated, porous, spherical, silica particles, 5 – 20 µm in diameter | Chiral OJ |
| L90 | Amylose tris-[(S)-alpha-methylbenzylcarbamate] coated on porous, spherical silica particles, 3 to 10 µm in diameter | Chiral AS |
| L118 | Aqueous polymerized C18 groups on silica particles, 1.2 to 5 μm in diameter | PAH |
