SMB (Simulated Moving Bed) Chromatography System

Innovative Solutions for Efficient Separation

Biovanix SMB (Simulated Moving Bed) Chromatography System is an advanced continuous chromatography separation technology widely used in chemical, pharmaceutical, and food industries. By simulating the movement of the stationary phase, the SMB system achieves highly efficient and stable separation effects, significantly improving production efficiency and product quality.

Biovanix SMB system connects multiple chromatography columns into a loop system, divided into functional zones such as adsorption, elution, and regeneration. By periodically switching valves, the stationary phase is made to “move” relative to the mobile phase, achieving continuous sample injection, separation, and collection.

Ventajas

Alta eficacia

The SMB system can increase production efficiency by 3-8 times compared to traditional single-column chromatography.

Low Solvent Consumption

Optimized separation processes reduce solvent usage by 20-50%.

High Purity and High Recovery Rate

Product purity can reach nearly 100%, with a recovery rate of up to 100%.

Continuous Operation

Achieves 24/7 uninterrupted operation, reducing labor costs.

Especificaciones técnicas

Number of Columns：4-12.

Number of DAC Columns：2-4.

Flow Rate Range：0.1-10 L/min.

Operating Pressure：0.1-10 MPa.

Temperature Range：5-80°C.

Customization

We offer comprehensive technical support and services, including system installation, commissioning, training, and after-sales maintenance, to ensure that customers can operate the SMB system smoothly.

1. Separation Efficiency

Purity: SMB chromatography is designed to achieve high-purity separation, with product purity often reaching above 99%.
Recovery Rate: With optimized operating conditions, the recovery rate in SMB chromatography can approach 100%.

2. Operating Parameters

Caudal: The flow rate of the mobile phase is a critical parameter, typically optimized based on the separation target. The flow rate range is generally between 0.1-10 L/min.
Switching Time: The valve switching time is an important operational parameter in SMB systems, determining the “movement” speed of the stationary phase relative to the mobile phase. The selection of switching time needs to be optimized based on the adsorption characteristics of the substances being separated.
Feed Rate: The amount of feed introduced into the system directly affects separation efficiency and the system’s production capacity.

3. System Configuration

Number of Columns: SMB systems typically consist of 4-12 chromatographic columns.
Column Dimensions: Including column length, diameter, and packing volume, these parameters influence separation effectiveness and the system’s processing capacity.

4. Economic Indicators

Solvent Consumption: Compared to traditional batch chromatography, SMB chromatography can reduce solvent usage by 20-50%.
Adsorbent Usage: SMB chromatography can save up to 50% of adsorbent.
Operating Cost: Long-term operating costs can be reduced by 50%, primarily due to the savings in solvent and adsorbent usage.

5. Control and Optimization

Control Strategy: Modern SMB systems often employ advanced control strategies, such as Model Predictive Control (MPC) and Moving Horizon Estimation (MHE), to achieve efficient separation.
Optimization Parameters: These include isotherm models, mass transfer resistances, and cycle switching times.

6. Other Indicators

Temperature Range: Typically between 5-80°C, depending on the nature of the substances being separated.
Rango de presión: Operating pressure is generally between 0.1-10 MPa.

Aplicación

Chemical Industry

Separation of xylene isomers.

Pharmaceutical Industry

Chiral drug separation.

Food Industry

Separation of fructose and glucose.

¿Por qué elegir Biovanix?

Conocimientos y experiencia

Con años de experiencia en la industria de transferencia de fluidos, tenemos la experiencia y el conocimiento para ofrecerle las mejores soluciones para sus necesidades específicas. Nuestro equipo de profesionales se dedica a ayudarle a elegir la bomba de émbolo buzo adecuada para su aplicación y a garantizar el éxito de su implantación.

Calidad y fiabilidad

Nos comprometemos a ofrecerle productos y servicios de la máxima calidad. Nuestra bomba de émbolo buzo está diseñada y fabricada con los más altos estándares, garantizando un rendimiento fiable y una larga durabilidad.

Atención al cliente

En [Nombre de su empresa], creemos que la satisfacción del cliente es nuestra máxima prioridad. Nuestro equipo de atención al cliente está siempre disponible para ayudarle con cualquier pregunta o problema que pueda tener. Desde el soporte técnico hasta el servicio posventa, estamos aquí para garantizarle una experiencia sin problemas ni complicaciones.

Soluciones a medida

Entendemos que cada aplicación es única, por lo que ofrecemos soluciones personalizadas adaptadas a sus necesidades específicas. Tanto si necesita una bomba de émbolo estándar como una solución personalizada, tenemos capacidad para satisfacer sus requisitos.

Póngase en contacto con nosotros

¿Está listo para experimentar la potencia y fiabilidad de nuestra bomba de émbolo buzo? Póngase en contacto con nosotros hoy mismo para obtener más información sobre nuestros productos y servicios. Nuestro equipo de expertos está listo para ayudarle y proporcionarle la mejor solución de transferencia de fluidos para su aplicación.