Verbrauchsmaterial für die Chromatographie
Stainless Steel HPLC Column Tubes
Precision-engineered 316L stainless steel column tubes for analytical, semi-preparative, and preparative liquid chromatography. Available in 10 inner diameters and 8 standard lengths — with full customization support.
10
ID Sizes
316L
Steel Grade
8+
STD. Lengths
∞
Sonderausstattungen
Analytical · Semi-Preparative · Preparative Columns
316L-Edelstahl
ISO Quality Standards
Custom Sizes Available
Technischer Support
Precision-Engineered Column Tubes for Every LC Scale
Biovanix manufactures high-quality stainless steel HPLC column tubes tailored to diverse application environments. Our column tubes are precision-machined from 316L Edelstahl — the industry-standard alloy renowned for its exceptional corrosion resistance, high-pressure tolerance, and broad chemical compatibility with HPLC solvents and mobile phases.
Whether you are running analytical separations on a 4.6mm ID column or scaling up to preparative purification with 50mm ID tubes, Biovanix provides the complete range of column hardware to support your workflow from method development to production.
Three Column Categories
We supply column tubes in three categories based on inner diameter and application scope:
- Analytical Column Tubes — ID 2.1–4.6mm for HPLC analysis and method development
- Semi-Preparative Column Tubes — ID 7.8–10mm for small-scale purification and compound isolation
- Preparative Column Tubes — ID 20–50mm for large-scale production and industrial applications
Multiple Frit Options
Biovanix offers different frit styles for analytical and semi-preparative column tubes. Each frit configuration is designed to provide optimal flow distribution and particle retention for specific particle size ranges, ensuring consistent chromatographic performance.
Product Specifications
Complete Size Range for Every LC Application
From narrow-bore analytical columns to wide-bore preparative tubes, Biovanix covers the full spectrum of HPLC column hardware needs.
Technical Specifications
Säulenmaterial | Edelstahl 316L |
Inner Diameter (ID) | 2.1, 3.0, 4.0, 4.6, 7.8, 10, 20, 21.2, 30, 50 mm |
Standard Lengths | 20, 30, 50, 100, 150, 250, 300, 500 mm |
Custom Lengths | Available upon request |
Column Categories | Analytical · Semi-Preparative · Preparative |
Frit Options | Multiple styles for analytical and semi-prep columns |
Available Sizes
Inner Diameter (mm)
2.1
3.0
4.0
4.6
7.8
10
20
21.2
30
50
Standard Length (mm)
20
30
50
100
150
200
250
300
500
Need a non-standard size?
We accept custom orders for any dimension. Contact us →
SS Frits for HPLC Column
Distribution Plate for HPLC Column
Different Column Frits For Different Applications
To meet diverse user needs, Biovanix developed three types of sieve plate connectors: sheet-type, PEEK-jacketed, and stainless steel hard-seal sieve plates. The sheet-type is the earliest generation design. The PEEK-jacketed is an optimized upgrade of the sheet-type: when the column head is tightened, the outer PEEK ring deforms under pressure, fills gaps between the metal connector and column tube to ensure a leak-free seal. The stainless steel hard-seal is designed for ultra-high-pressure chromatography columns, with a surface roughness of Ra < 0.2 on its hard-seal contact surface, overcoming PEEK material’s insufficient pressure resistance.
Preparative HPLC Column Tubing
Biovanix has developed threaded column tubes and flanged column tubes tailored for distinct application scenarios. Threaded column tubes feature convenient assembly and disassembly with rapid operability, making them suitable for small-diameter, medium-low pressure applications that require frequent maintenance in laboratory settings. Flanged column tubes, which achieve uniform stress distribution via multiple bolts, exhibit a high pressure-bearing capacity, minimal dead volume, and enhanced structural wear resistance. This type represents the dominant solution for industrial scale-up, large-diameter, and high-pressure preparative separation processes.
Threaded Column Tubing
Flanged Column Tubing
Why Choose Biovanix
Built for Performance, Designed for Reliability
Every Biovanix column tube is manufactured under strict quality controls to deliver the dimensional accuracy, surface finish, and chemical integrity your separations demand.
316L Alloy Superiority
316L stainless steel provides exceptional resistance to corrosion from acidic and organic mobile phases, ensuring long service life even under aggressive HPLC conditions.
Precision Machining
Tight dimensional tolerances on ID, OD, and length ensure reliable fitting with standard HPLC fittings and frits. Consistent quality from tube to tube, batch to batch.
High Pressure Rating
316L construction withstands the high pressures encountered in analytical and preparative HPLC systems, providing a safe and reliable column hardware platform.
Full Size Range
From 2.1mm ID analytical capillaries to 50mm ID preparative tubes — one supplier covers your entire workflow from method development to production scale.
Multiple Frit Styles
Different frit configurations available for analytical and semi-preparative columns, optimized for various particle sizes and application requirements.
Custom Service
Non-standard dimensions, special end fittings, or unique frit requirements — our engineering team works with you to deliver exactly what your application needs.
Application Guide
From Lab Analysis to Industrial Production
Biovanix stainless steel column tubes serve the full spectrum of liquid chromatography workflows across pharmaceutical, biotech, food safety, environmental, and chemical industries.
01 Pharmaceutical QC & Analysis
Use 2.1–4.6mm ID analytical columns for drug substance characterization, dissolution testing, impurity profiling, and content uniformity analysis per pharmacopeial methods.
02 Method Development & Screening
Narrow-bore columns (2.1mm, 3.0mm ID) minimize solvent consumption during method scouting, while 4.6mm ID provides seamless transfer to preparative scale.
03 Natural Product Isolation
Semi-preparative columns (7.8–10mm ID) efficiently isolate active compounds from botanical extracts, traditional medicine, and marine natural products.
04 Preparative Purification
Large-bore preparative tubes (20–50mm ID) handle kilogram-scale production of high-value intermediates, peptides, and fine chemicals with high recovery.
05 Food Safety & Environmental Testing
Reliable 4.6mm ID analytical columns for pesticide residue analysis, mycotoxin detection, veterinary drug screening, and environmental pollutant monitoring.
06 Custom & OEM Integration
Partner with Biovanix for custom column tube manufacturing — from prototype to volume production — with dedicated engineering support and competitive pricing.
Selection Guide
Choosing the Right Column Tube for Your Application
Match the column tube inner diameter and category to your separation scale and objectives.
| Category | ID Range | Typical Use | Durchflussmenge | Scale |
|---|---|---|---|---|
| Analytical | 2.1 – 4.6 mm | Quality control, method development, assay | 0.2 – 2.0 mL/min | μg – mg |
| Semi-Preparative | 7.8 – 10 mm | Compound isolation, small-scale purification | 2 – 10 mL/min | mg – g |
| Präparativ | 20 – 50 mm | Large-scale purification, production | 10 – 100+ mL/min | g – kg |
Need help choosing? If you’re unsure which column tube dimensions are right for your application, our technical team can help. Share your separation requirements and we’ll recommend the optimal configuration. Get expert advice →
Product Dedscription
Ready to Order Stainless Steel Column Tubes?
Share your specifications — ID, length, frit type, and quantity — and receive a competitive quote within 24 hours. Custom sizes welcome.
Complete Your Setup
Related Chromatography Consumables
Biovanix offers a complete range of HPLC consumables to complement your column tubes — from guard columns to fittings.
HPLC Guard Columns
Protect your analytical columns from contamination and extend column lifetime. Available in 4.6×10mm, 10×10mm, and 20×10mm. Custom appearance for 4.6×10mm.
PEEK HPLC Column Tubes
Metal-ion-free PEEK column tubes with PE frits. Smooth inner walls for zero contamination. ID: 2.1mm, 4.6mm. Lengths: 50, 100, 150mm. Custom sizes available.
In-line Filters
Designed for semi-preparative and preparative LC systems. Five sizes available: 10mm, 20mm, 30mm, 50mm, and 68mm. Protect downstream equipment.
Chromatography Accessories
Premium PEEK, POM, and PE fittings — gaskets, connectors, and stoppers. Custom manufacturing per your drawings. Complete hardware solutions.
View More →
Frequently Asked Questions
Everything You Need to Know
Answers to common questions about Biovanix stainless steel HPLC column tubes and chromatography consumables.
What is the material specification of Biovanix stainless steel HPLC column tubes?
Biovanix stainless steel HPLC column tubes are manufactured from 316L Edelstahl, which offers superior corrosion resistance, high pressure tolerance, and excellent chemical compatibility with common HPLC solvents and mobile phases. The low-carbon “L” grade minimizes carbide precipitation during welding and ensures consistent performance.
What inner diameter sizes are available?
Biovanix offers stainless steel HPLC column tubes in 10 standard inner diameters: 2.1mm, 3.0mm, 4.0mm, 4.6mm, 7.8mm, 10mm, 20mm, 21.2mm, 30mm, and 50mm. This range covers analytical (2.1–4.6mm), semi-preparative (7.8–10mm), and preparative (20–50mm) applications. Custom inner diameters are available upon request.
Can I order custom-sized stainless steel column tubes?
Yes. In addition to standard lengths of 20mm, 30mm, 50mm, 100mm, 150mm, 250mm, 300mm, and 500mm, Biovanix accepts custom orders for non-standard dimensions. Whether you need a specific length, unique end fittings, or special frit configurations, our engineering team can accommodate your requirements. Contact us with your specifications for a quote.
What is the difference between analytical, semi-preparative, and preparative column tubes?
Analytical column tubes (typically 2.1–4.6mm ID) are designed for sample analysis, quality control, and method development. Semi-preparative columns (7.8–10mm ID) bridge analytical and preparative workflows, enabling small-scale purification and compound isolation. Preparative columns (20–50mm ID) are built for large-scale compound isolation and production, handling gram to kilogram quantities.
What frit options are available for Biovanix stainless steel column tubes?
Biovanix provides multiple frit styles for analytical and semi-preparative column tubes. Different frit configurations are optimized for various particle size ranges and application requirements. The appropriate frit ensures uniform flow distribution, efficient particle retention, and consistent chromatographic performance. Contact our technical team for specific frit recommendations based on your particle size and application.
When should I choose stainless steel column tubes over PEEK?
Stainless steel 316L column tubes are the default choice for most routine HPLC applications, offering excellent pressure resistance, broad chemical compatibility, and long-term durability. PEEK column tubes are preferred for metal-sensitive applications such as protein/peptide analysis, ion chromatography, or any workflow where metal ion contamination must be avoided. Biovanix offers both options — contact us if you need help deciding.
Let's Discuss Your Column Tube Requirements
Whether you need standard sizes or custom dimensions, Biovanix delivers quality stainless steel HPLC column tubes with fast turnaround and competitive pricing.
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