High-Pressure Pneumatic HPLC Column Packing System for Analytical & Semi-Prep Chromatography

Achieve uniform bed density with constant pneumatic pressure. The Isoplex system utilizes compressed air or nitrogen to generate a stable, continuous downward force — packing Silica gel and Polymer resins tightly and uniformly into columns from 2.0 mm to 50 mm ID.

19,000

Max PSI

2–50

mm ID Range

0

Electricity Needed

Explosion-Proof Design

1-Year Warranty

Free Online Training

Free Replacement Hardware

Why This Packing System Fits Your Lab

Unlike mechanical pumps that may introduce pulsation, the Isoplex system uses compressed gas to deliver a constant, pulse-free force — critical for reproducible chromatography column packing.

Prevent Voids & Channeling

The steady pneumatic drive eliminates pressure spikes, significantly reducing the risk of channeling or voids inside the column bed. Every pack is uniform and reproducible.

Vielseitige Anwendung

Ideal for packing analytical to semi-preparative and preparative columns. Supports inner diameters from 2.0 mm to 50 mm and lengths from 20 mm to 500 mm.

Safety & Simplicity

Operates purely on compressed gas sources (8 bar input), making it spark-free and safe for use with flammable organic solvents like Methanol or Acetonitrile.

No Electricity Required

Driven entirely by compressed air or nitrogen. Place it anywhere — on the lab bench, in a fume hood, or on a rolling cart. No power outlet needed.

Konsistente Reproduzierbarkeit

Constant pneumatic pressure ensures every column is packed under identical conditions. Achieve higher theoretical plate numbers and sharper peak shapes consistently.

Customizable Configuration

Seven types of homogenate tanks available for different column sizes. Custom tanks, tubings, connectors, and packing material support provided based on your specific needs.

Isoplex HPLC Column Packing System — Parameters

Complete technical specifications of the Isoplex pneumatic column packing system, designed for analytical through preparative HPLC column packing.

Produkt	Isoplex HPLC-Säulen-Packungssystem
Spalten-ID	2,0/3,0/4,0/4,6/10/20/30/50 mm
Column Length	20-500mm
Input Power	Compressed Air / Nitrogen (No electricity required)
Ausgangsdruck	0-19000 psi
Durchflussmenge	3,3 l/min
Ausgangsleistung	2 PS
Zylinder	Doppel
Benetzte Materialien	316L Stainless Steel, PTFE, PEEK (fully solvent resistant)

Standard & Optional Configuration

Configure the Isoplex system to match your laboratory’s packing requirements. Standard packages include all essential components; optional accessories extend capability for higher throughput or specialized applications.

Standardteile	Optionale Teile
Bedienungsanleitung	Luftkompressor
Hauptmaschine	Luftreinigungssystem
Bedienfeld	Homogenatbehälter
Stützen	Säulenverbindung (ID 2.1-50mm)
Edelstahlverbindungen	Leere HPLC-Säulen (ID 2,1-50mm)
Schläuche verbinden	Packmaterialien

Homogenate Tank Volume by Column ID

Homonatenpanzer	Estimated Volume
For 2.1mm I.D.	5ml
For 4.6mm I.D.	25ml
For 10mm I.D.	80ml
For 20mm I.D.	420ml
For 30mm I.D.	590ml
For 50mm I.D.	1800ml

* Homonate Tanks can be customized based on practical application.

Advantages For Isoplex Column Packing System

Engineered for safety, portability, and versatility — the Isoplex system sets a new standard for pneumatic HPLC column packing in research and production laboratories.

Safety First

Powerless Design & Emergency Cut-off Valves

Isoplex column packing system is driven by compressed air. No need for power supply. You can put it everywhere you like.
This machine also has emergency cut-off valves to deal with emergencies.

Compact

Small in size, Easy to transport

The size for Isoplex column packing system is about 60cm(L) * 40cm(W) * 30cm(H). It can be put on the labaratory table, fuming cupboard, or even a rolling cart. Gross weight is about 35kg.
We also provide laboratory-grade small-sized integrated air compressor 52cm(L)*61cm(H)*102cm(H) which can improve the utilization rate of space.

Low Noise

Reduce Noise

We are equipped with a silencer and a sound-absorbing sponge inside of the main machine to protect labour health. When using this machine, labourers do not need to wear noise-cancelling headphones or any other ear-protection gear.

Versatile

Wide range of application

Isoplex column packing system can pack almost all kind of HPLC columns. Innerdiameter from 2.0mm to 50mm, length from 20mm to 500mm.
Seven types of homonate tanks for different types of HPLC columns. Or customized based on your needs.

Tailored

Maßgeschneiderter Service

We provide customized service based on different needs, including support for homonate tanks, tubings, connectors, packing materials.

Ready to Upgrade Your Column Packing Process?

Tell us about your application — column size, media type, and throughput — and we’ll recommend the ideal Isoplex configuration.

System Components

Every component of the Isoplex system is designed for durability, solvent resistance, and ease of use.

Hauptmaschine

The core pneumatic packing unit with double air cylinders, delivering up to 19,000 psi output pressure. Fully solvent-resistant wetted materials.

Small Homonate Tank

Designed for analytical and small semi-prep columns (2.1–10 mm ID). Ensures slurry stability during the packing process for reproducible results.

Big Homonate Tank

Built for preparative-scale columns (20–50 mm ID) with volumes up to 1,800 ml. Custom sizes available for specialized applications.

Video

Operation for HPLC column packing System

(old version)

Product Description (New Version)

Compatible HPLC Columns & Chromatography Accessories

Biovanix provides a complete one-stop solution — from column packing equipment to empty column tubes, guard columns, and fittings. All products are designed for seamless compatibility with the Isoplex system.

Silica gel for HPLC

Biovanix silica-gel packing materials offering a full range from analytical to preparative scales.

Reversed-phase Chromatography: C18, C8, C4, Phenyl

Normal-phase Chromatography: SiO2, NH2/Amino, CN/Cyano, Diol

Particel Size: 5um / 10um / 30um / 50um

Stainless Steel HPLC Column Tubes

High-precision 316L stainless steel column tubes for analytical, semi-preparative, and preparative liquid chromatography. Multiple frit styles available.

Material: 316L-Edelstahl

ID: 2.1 / 3.0 / 4.0 / 4.6 / 7.8 / 10 / 20 / 21.2 / 30 / 50 mm

Länge: 20 / 30 / 50 / 100 / 150 / 250 / 300 / 500 mm (customizable)

Types: Analytical / Semi-prep / Preparative

Guard Columns For HPLC

Protect your analytical columns from particulate contamination and extends column lifetime. Available in three standard sizes with customizable appearance.

PEEK-Säulenrohre

Premium PEEK material with PE frits. Zero metal ions, smooth and clean inner wall — ideal for metal-sensitive applications and biochromatography.

Material: PEEK tube + PE frit

ID: 2.1 / 4.6 mm

Länge: 50 / 100 / 150 mm (customizable)

Feature: Zero metal ions

Bestellinformationen

Complete part numbers for the Isoplex system and homogenate tanks. Contact us for custom configurations and bulk pricing.

	Produktionsnummer
Hauptmaschine	Z20004650
Homonatenpanzer	Für 2,1 mm	Für 4,6 mm	Für 10mm	Für 20 mm	Für 30mm	Für 50mm
Homonatenpanzer	Z0502115	Z0504630	Z0501030	Z0502030	Z0503030	Z0505030

Homanate tanks are customised based on actual needs. Please contact us for details >>

Frequently Asked Questions (FAQ)

Common questions about the Isoplex HPLC column packing system, compatibility, and ordering.

How does a pneumatic HPLC packing system improve column efficiency compared to manual packing?

A pneumatic system improves efficiency by applying consistent, high-pressure force that manual packing cannot achieve. The compressed air drives the slurry into the column at a constant rate, ensuring a tightly packed bed. This results in sharper peak shapes, higher theoretical plate numbers, and better resolution in your chromatograms.

What gas source is required to operate this packing system?

The system requires a standard laboratory compressed air supply or a Nitrogen gas cylinder. It typically operates with an input pressure of 8 bar (approx. 115 psi), which the system’s internal booster amplifies to the required high hydraulic pressure (e.g., 6,000 – 10,000 psi) for packing.

Can this system pack both silica and polymer-based media?

Yes, this system is compatible with all standard HPLC stationary phases, including Silica, C18, and Polymer resins. The pressure can be regulated to suit the fragility of specific media, preventing particle crushing while ensuring sufficient compression.

Is this packing station safe for use with explosive solvents?

Yes. Since the system is entirely pneumatically driven and requires no electrical power, it is intrinsically safe and explosion-proof. It is ideal for packing processes involving flammable solvents like Hexane, Acetone, or Acetonitrile.

What column sizes can the Isoplex system accommodate?

The Isoplex system supports column inner diameters from 2.0 mm to 50 mm and lengths from 20 mm to 500 mm, covering analytical, semi-preparative, and preparative HPLC columns. Seven standard homogenate tank sizes are available, and custom configurations can be arranged based on your application requirements.

Does Biovanix supply empty HPLC column tubes and chromatography accessories?

Yes. Biovanix provides a complete one-stop solution including 316L stainless steel HPLC column tubes (ID 2.1–50 mm), PEEK column tubes, guard columns, inline filters, and chromatography fittings (PEEK, POM, PE). All accessories can be customized according to customer drawings.

Let's Build Your Ideal Column Packing Setup

Whether you need the Isoplex system alone or a complete solution with column tubes, guard columns, and fittings — Biovanix is your single-source partner.